Discussion
Diagnosis With Brief Discussion
- Diagnosis
- Lung metastases from sarcoma
- Radiologic Findings
- Chest radiograph shows multiple variable-sized nodules and masses in both lungs. Contrast-enhanced CT scan of the chest shows multiple variable-sized hypervascular nodules and masses in the lungs. There are dilated, tortuous, and tubular enhancing structures within these lesions.
Mass in the right lower lobe was histologically confirmed as sarcoma of undifferentiated type, favoring metastatic sarcoma. On immunohistochemical study, vimentin and CD 10 were positive, while other markers, such as CK, p63, inhibin-alpha, alpha-SMA, CD31 and desmin, were negative. During work up for primary tumor, uterine mass of 6 cm was detected and suspected as sarcoma, but histologic diagnosis was not obtained since patient was discharged as hopeless.
- Brief Review
- Sometimes dilated, tortuous, and tubular enhancing structures within metastatic nodules are observed at contrast-enhanced CT. These structures are engorged tumor vessels that suggest the hypervascular nature of the metastatic nodules. Such findings are observed in cases of a metastasis from a sarcoma such as an alveolar soft-part sarcoma or a leiomyosarcoma.
- References
- Atypical Pulmonary Metastases: Spectrum of Radiologic Findings. Seo JB, Im JG, Goo JM, Chung MJ, Kim MY. Radiographics. 2001 Mar-Apr;21(2):403-17. Review.RadioGraphics 2001; 21:403–417
- Keywords
- Lung, Neoplasm_Malignant, Metastasis,